• Claudin 2 mouse mAb(PT0311)
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Upingbio

YP-Ab-16871-10UL

Claudin 2 mouse mAb(PT0311)

Claudin 2 mouse mAb(PT0311)

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  • Reaction species: Human
  • Gene Name: CLDN2 PSEC0059 SP82 UNQ705/PRO1356
  • Protein name: Claudin 2
  • Molecular weight (DA): 25kD
  • Immunogen: Synthesized peptide derived from human Claudin 2
  • Specificity: This antibody detects endogenous levels of human Claudin 2
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Mouse, Monoclonal/IgG2b, Kappa
  • Dilution ratio: IHC-p 1:100-300，WB 1:500-2000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: Claudin-2 (SP82)
  • Background: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010],
  • Function: function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
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