• SCP-3 Polyclonal Antibody
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Upingbio

YP-Ab-16788-100UL

SCP-3 Polyclonal Antibody

SCP-3 Polyclonal Antibody

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  • Gene Name: SYCP3
  • Immunogen: Synthesized peptide derived from the Internal region of human SCP-3.
  • Specificity: SCP-3 Polyclonal Antibody detects endogenous levels of SCP-3 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: SYCP3; SCP3; Synaptonemal complex protein 3; SCP-3
  • Background: This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010],
  • Function: disease:Defects in SYCP3 are associated with azoospermia due to perturbations of meiosis [MIM:270960].,function:Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development.,similarity:Belongs to the XLR/SYCP3 family.,subcellular location:In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.,subunit:Interacts with SYCP2.,tissue specificity:Testis-specific.,
  • Species: Human;Mouse
  • Range: WB;ELISA;IHC
  • Protein: Synaptonemal complex protein 3
  • DA: 27kD
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