• NuMA Polyclonal Antibody
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Upingbio

YP-Ab-16756-100UL

NuMA Polyclonal Antibody

NuMA Polyclonal Antibody

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  • Gene Name: NUMA1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human NUMA1. AA range:334-383
  • Specificity: NuMA Polyclonal Antibody detects endogenous levels of NuMA protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: NUMA1; NUMA; Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen
  • Background: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
  • Function: function:May be a structural component of the nucleus.,subcellular location:Dissociates from condensing chromosomes during early prophase, before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Nuclear mitotic apparatus protein 1
  • DA: 240kD
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