• CdcA7 Polyclonal Antibody
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Upingbio

YP-Ab-16694-100UL

CdcA7 Polyclonal Antibody

CdcA7 Polyclonal Antibody

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  • Gene Name: CDCA7
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CDCA7. AA range:141-190
  • Specificity: CdcA7 Polyclonal Antibody detects endogenous levels of CdcA7 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CDCA7; JPO1; Cell division cycle-associated protein 7; Protein JPO1
  • Background: cell division cycle associated 7(CDCA7) Homo sapiens This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
  • Function: function:Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.,induction:Activated by MYC and possibly E2F1.,miscellaneous:CDCA7 expression is correlated with MYC expression in lymphoblastoid, lymphoma and breast cancer cell lines.,tissue specificity:Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: Cell division cycle-associated protein 7
  • DA: 43kD
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