• APC5 Polyclonal Antibody
1 1

Upingbio

YP-Ab-16660-100UL

APC5 Polyclonal Antibody

APC5 Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: ANAPC5
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
  • Specificity: APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
  • Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],
  • Function: function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the APC5 family.,similarity:Contains 4 TPR repeats.,subunit:The APC/C is composed of at least 11 subunits.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Anaphase-promoting complex subunit 5
  • DA: 85kD
View full details