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SKU:YP-Ab-16529-100UL
CD298 Polyclonal Antibody
CD298 Polyclonal Antibody
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- Gene Name: ATP1B3
- Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human ATP1B3. AA range:222-271
- Specificity: CD298 Polyclonal Antibody detects endogenous levels of CD298 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: ATP1B3; Sodium/potassium-transporting ATPase subunit beta-3; Sodium/potassium-dependent ATPase subunit beta-3; ATPB-3; CD298
- Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subun
- Function: function:This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.,similarity:Belongs to the X(+)/potassium ATPases subunit beta family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Composed of three subunits: alpha (catalytic), beta and gamma.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Sodium/potassium-transporting ATPase subunit beta-3
- DA: 36kD
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