• Na+ CP type IIβ Polyclonal Antibody
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Upingbio

YP-Ab-16471-100UL

Na+ CP type IIβ Polyclonal Antibody

Na+ CP type IIβ Polyclonal Antibody

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Size
  • Gene Name: SCN2B
  • Immunogen: The antiserum was produced against synthesized peptide derived from human SCN2B. AA range:71-120
  • Specificity: Na+ CP type IIβ Polyclonal Antibody detects endogenous levels of Na+ CP type IIβ protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: SCN2B; Sodium channel subunit beta-2
  • Background: The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. [provided by RefSeq, Jul 2015],
  • Function: function:Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,subunit:The sodium channel consists of a pore-forming alpha subunit, beta-1 and beta-2 subunits. Beta-1 is non-covalently associated with alpha, while beta-2 is covalently linked by disulfide bonds. Interaction with SCN10A and TNR.,tissue specificity:Brain specific.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA;IHC
  • Protein: Sodium channel subunit beta-2
  • DA: 24kD
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