• Rho H Polyclonal Antibody
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Upingbio

YP-Ab-16244-100UL

Rho H Polyclonal Antibody

Rho H Polyclonal Antibody

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  • Gene Name: RhoH
  • Immunogen: The antiserum was produced against synthesized peptide derived from human RhoH. AA range:141-190
  • Specificity: Rho H Polyclonal Antibody detects endogenous levels of Rho H protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: RHOH; ARHH; TTF; Rho-related GTP-binding protein RhoH; GTP-binding protein TTF; Translocation three four protein
  • Background: The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013],
  • Function: disease:A chromosomal aberration involving RHOH is found in a non-Hodgkin lymphoma cell line. Translocation t(3;4)(q27;p11) with BCL6.,similarity:Belongs to the small GTPase superfamily. Rho family.,tissue specificity:Transcribed only in hemopoietic cells.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Rho-related GTP-binding protein RhoH
  • DA: 21kD
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