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SKU:YP-Ab-16222-100UL
Ran BP-17 Polyclonal Antibody
Ran BP-17 Polyclonal Antibody
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- Gene Name: RANBP17
- Immunogen: The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194
- Specificity: Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: RANBP17; Ran-binding protein 17
- Background: RAN binding protein 17(RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002],
- Function: function:May function as a nuclear transport receptor.,similarity:Belongs to the exportin family.,subunit:Binds to nucleoporins and the GTP-bound form of Ran.,tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.,
- Species: Human;Mouse
- Range: WB;IHC
- Protein: Ran-binding protein 17
- DA: 125kD
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