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Upingbio
SKU:YP-Ab-16175-100UL
Gα t2 Polyclonal Antibody
Gα t2 Polyclonal Antibody
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- Gene Name: GNAT2
- Immunogen: The antiserum was produced against synthesized peptide derived from human GNAT2. AA range:1-50
- Specificity: Gα t2 Polyclonal Antibody detects endogenous levels of Gα t2 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: GNAT2; GNATC; Guanine nucleotide-binding protein G(t) subunit alpha-2; Transducin alpha-2 chain
- Background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008],
- Function: disease:Defects in GNAT2 are the cause of achromatopsia type 4 (ACHM4) [MIM:139340]. Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination.,function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,tissue specificity:Retinal rod outer segment.,
- Species: Human;Mouse
- Range: WB;IHC;IF;ELISA
- Protein: Guanine nucleotide-binding protein G(t) subunit alpha-2
- DA: 40kD
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