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Upingbio
SKU:YP-Ab-16165-100UL
GIMAP5 Polyclonal Antibody
GIMAP5 Polyclonal Antibody
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- Gene Name: GIMAP5
- Immunogen: The antiserum was produced against synthesized peptide derived from human GIMAP5. AA range:231-280
- Specificity: GIMAP5 Polyclonal Antibody detects endogenous levels of GIMAP5 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: GIMAP5; IAN4L1; IAN5; IMAP3; GTPase IMAP family member 5; Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; IAN-5; hIAN5; Immunity-associated protein 3
- Background: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010],
- Function: function:Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence.,similarity:Belongs to the IAN GTP-binding protein family.,tissue specificity:Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T-cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC;IF;ELISA
- Protein: GTPase IMAP family member 5
- DA: 35kD
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