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Upingbio
SKU:YP-Ab-16129-100UL
ARF6 Polyclonal Antibody
ARF6 Polyclonal Antibody
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- Gene Name: ARF6
- Immunogen: Synthesized peptide derived from ARF6 . at AA range: 30-110
- Specificity: ARF6 Polyclonal Antibody detects endogenous levels of ARF6 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: ARF6; ADP-ribosylation factor 6
- Background: ADP ribosylation factor 6(ARF6) Homo sapiens This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008],
- Function: function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.,similarity:Belongs to the small GTPase superfamily.,similarity:Belongs to the small GTPase superfamily. Arf family.,subunit:Interacts with ARHGAP21, ASAP2, HERC1, PIP5K1C and UACA.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: ADP-ribosylation factor 6
- DA: 20kD
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