• EF-2 Monoclonal Antibody
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Upingbio

YP-Ab-16103-53UL

EF-2 Monoclonal Antibody

EF-2 Monoclonal Antibody

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  • Reaction species: Human;Mouse;Rat
  • Gene Name: EEF2
  • Protein name: Elongation factor 2
  • Immunogen: Purified recombinant human EF-2 protein fragments expressed in E.coli.
  • Specificity: EF-2 Monoclonal Antibody detects endogenous levels of EF-2 protein.
  • Composition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.
  • Purification process: Affinity purification
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: EEF2; EF2; Elongation factor 2; EF-2
  • Background: This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008],
  • Function: function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,
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