• ANGP2 Polyclonal Antibody
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Upingbio

YP-Ab-16093-100UL

ANGP2 Polyclonal Antibody

ANGP2 Polyclonal Antibody

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  • Gene Name: ANGPT2
  • Immunogen: Synthesized peptide derived from human ANGP2
  • Specificity: This antibody detects endogenous levels of human ANGP2
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000, ELISA(peptide)1:5000-20000
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Angiopoietin-2 (ANG-2)
  • Background: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • Function: function:Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.,online information:Angiopoietin entry,similarity:Contains 1 fibrinogen C-terminal domain.,
  • Species: Human;Rat;Mouse;
  • Range: WB; ELISA
  • Protein: ANGP2
  • DA: 55kD
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