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Upingbio
SKU:YP-Ab-16067-100UL
GDF-7 Polyclonal Antibody
GDF-7 Polyclonal Antibody
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- Gene Name: GDF7
- Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370
- Specificity: GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: GDF7; Growth/differentiation factor 7; GDF-7
- Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],
- Function: function:May play an active role in the motor area of the primate neocortex.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: Growth/differentiation factor 7
- DA: 47kD
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