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Upingbio
SKU:YP-Ab-16060-100UL
GDF-3 Polyclonal Antibody
GDF-3 Polyclonal Antibody
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- Gene Name: GDF3
- Immunogen: Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
- Specificity: GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: GDF3; Growth/differentiation factor 3; GDF-3
- Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],
- Function: online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Growth/differentiation factor 3
- DA: 41kD
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