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Upingbio
SKU:YP-Ab-16039-100UL
Eotaxin Polyclonal Antibody
Eotaxin Polyclonal Antibody
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- Gene Name: CCL11
- Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CCL11. AA range:41-90
- Specificity: Eotaxin Polyclonal Antibody detects endogenous levels of Eotaxin protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: CCL11; SCYA11; Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
- Background: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014],
- Function: function:In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.,induction:By TNF-alpha, interleukin-1 alpha and interferon gamma.,online information:CCL11 entry,PTM:O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.,similarity:Belongs to the intercrine beta (chemokine CC) family.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Eotaxin
- DA: 11kD
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