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Upingbio

SKU:YP-Ab-16030-100UL

Cerberus Polyclonal Antibody

Cerberus Polyclonal Antibody

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  • Gene Name: CER1
  • Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CER1. AA range:91-140
  • Specificity: Cerberus Polyclonal Antibody detects endogenous levels of Cerberus protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CER1; DAND4; Cerberus; Cerberus-related protein; DAN domain family member 4
  • Background: This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008],
  • Function: function:Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.,PTM:N-glycosylated.,sequence caution:Translated as Ser.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Forms monomers and predominantly dimers.,
  • Species: Human;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Cerberus
  • DA: 30kD
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