• ET-1 Polyclonal Antibody
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Upingbio

YP-Ab-15988-100UL

ET-1 Polyclonal Antibody

ET-1 Polyclonal Antibody

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  • Gene Name: EDN1
  • Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
  • Specificity: ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p: 100-300.WB: 1/500 - 1/2000. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: EDN1; Endothelin-1; Preproendothelin-1; PPET1
  • Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
  • Function: function:Endothelins are endothelium-derived vasoconstrictor peptides.,online information:Endothelin entry,similarity:Belongs to the endothelin/sarafotoxin family.,tissue specificity:Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Endothelin-1
  • DA: 25kD
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