• VEGF-B Polyclonal Antibody
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Upingbio

YP-Ab-15979-100UL

VEGF-B Polyclonal Antibody

VEGF-B Polyclonal Antibody

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  • Gene Name: VEGFB
  • Immunogen: The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140
  • Specificity: VEGF-B Polyclonal Antibody detects endogenous levels of VEGF-B protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
  • Background: This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011],
  • Function: alternative products:Additional isoforms seem to exist,function:Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.,PTM:VEGF-B186 is O-glycosylated.,similarity:Belongs to the PDGF/VEGF growth factor family.,subcellular location:Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.,subunit:Homodimer; disulfide-linked. Can also form heterodimer with VEGF.,tissue specificity:Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Vascular endothelial growth factor B
  • DA: 21kD
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