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Upingbio
SKU:YP-Ab-15976-100UL
Urocortin Polyclonal Antibody
Urocortin Polyclonal Antibody
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- Gene Name: UCN
- Immunogen: The antiserum was produced against synthesized peptide derived from human Urocortin. AA range:71-120
- Specificity: Urocortin Polyclonal Antibody detects endogenous levels of Urocortin protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: UCN; Urocortin
- Background: This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016],
- Function: function:Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF Receptor types 1, 2-alpha, and 2-beta.,similarity:Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.,
- Species: Human;Mouse;Rat
- Range: IHC;IF;ELISA
- Protein: Urocortin
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