• GDF-8 Polyclonal Antibody
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Upingbio

YP-Ab-15915-100UL

GDF-8 Polyclonal Antibody

GDF-8 Polyclonal Antibody

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  • Gene Name: MSTN
  • Immunogen: The antiserum was produced against synthesized peptide derived from human GDF-8. AA range:38-87
  • Specificity: GDF-8 Polyclonal Antibody detects endogenous levels of GDF-8 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin
  • Background: myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],
  • Function: function:Acts specifically as a negative regulator of skeletal muscle growth.,online information:Myostatin entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity.,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: Growth/differentiation factor 8
  • DA: 43kD
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