• BMP-3 Polyclonal Antibody
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Upingbio

YP-Ab-15877-100UL

BMP-3 Polyclonal Antibody

BMP-3 Polyclonal Antibody

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  • Gene Name: BMP3
  • Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-3. AA range:257-306
  • Specificity: BMP-3 Polyclonal Antibody detects endogenous levels of BMP-3 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: BMP3; BMP3A; Bone morphogenetic protein 3; BMP-3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin
  • Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],
  • Function: function:Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.,induction:Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts.,online information:Bone morphogenetic protein 3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in adult and fetal cartilage.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Bone morphogenetic protein 3
  • DA: 53kD
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