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Upingbio
SKU:YP-Ab-15844-10UL
IL-34 Monoclonal Antibody
IL-34 Monoclonal Antibody
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- Reaction species: Human
- Gene Name: IL34
- Protein name: Interleukin-34
- Immunogen: Purified recombinant fragment of human IL-34 expressed in E. Coli.
- Specificity: IL-34 Monoclonal Antibody detects endogenous levels of IL-34 protein.
- Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
- Source: Monoclonal, Mouse
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: Affinity purification
- Storage: -20°C/1 year
- Other Names: IL34; C16orf77; Interleukin-34; IL-34
- Background: Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008],
- Function: function:Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.,similarity:Belongs to the IL-34 family.,subunit:Homodimer.,tissue specificity:Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.,
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