• IL-1α Monoclonal Antibody
1 1

Upingbio

YP-Ab-15841-53UL

IL-1α Monoclonal Antibody

IL-1α Monoclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Reaction species: Human
  • Gene Name: IL1A
  • Protein name: Interleukin-1 alpha
  • Immunogen: Purified recombinant fragment of human IL-1a expressed in E. Coli.
  • Specificity: IL-1α Monoclonal Antibody detects endogenous levels of IL-1α protein.
  • Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: Affinity purification
  • Storage: -20°C/1 year
  • Other Names: IL1A; IL1F1; Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1
  • Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008],
  • Function: domain:The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.,function:Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.,online information:Interleukin-1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the IL-1 family.,subcellular location:The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.,subunit:Mono
View full details