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Upingbio
SKU:YP-Ab-15827-53UL
Cripto Monoclonal Antibody
Cripto Monoclonal Antibody
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- Reaction species: Human
- Gene Name: TDGF1
- Protein name: Teratocarcinoma-derived growth factor 1
- Immunogen: Purified recombinant fragment of human Cripto expressed in E. Coli.
- Specificity: Cripto Monoclonal Antibody detects endogenous levels of Cripto protein.
- Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
- Source: Monoclonal, Mouse
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: Affinity purification
- Storage: -20°C/1 year
- Other Names: TDGF1; CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1
- Background: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
- Function: function:Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.,similarity:Contains 1 EGF-like domain.,tissue specificity:Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.,
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