• COX-2 mouse mAb(ABT040)
1 1

Upingbio

YP-Ab-15569-10UL

COX-2 mouse mAb(ABT040)

COX-2 mouse mAb(ABT040)

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Reaction species: Human; Predict react with Mouse, Rat
  • Gene Name: PTGS2 COX2
  • Protein name: COX-2
  • Immunogen: Synthesized peptide derived from human COX-2
  • Specificity: The antibody can specifically recognize human COX-2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.133% sodium azide.
  • Source: Mouse, Monoclonal/IgG2b, Kappa
  • Dilution ratio: IHC-p 1:100-500, WB 1:200-1000, IF 1:100-500
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: Prostaglandin G/H synthase 2 (EC 1.14.99.1;Cyclooxygenase-2;COX-2;PHS II;Prostaglandin H2 synthase 2;PGH synthase 2;PGHS-2;Prostaglandin-endoperoxide synthase 2)
  • Background: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009],
  • Function: catalytic activity:Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group per subunit.,disease:Likely to play a role in inflammatory diseases such as rheumatoid arthritis.,function:May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.,induction:By cytokines and mitogens.,miscellaneous:This enzyme acts both as a dioxygenase and as a peroxidase.,miscellaneous:This enzyme is the target of nonsteroidal anti-inflammatory drugs such as aspirin.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the prostaglandin G/H synthase family.,similarity:Contains 1 EGF-like domain.,subunit:Homodimer.,
View full details