• CD3, CD3E mouse mAb(ABT295)
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Upingbio

YP-Ab-15552-53UL

CD3, CD3E mouse mAb(ABT295)

CD3, CD3E mouse mAb(ABT295)

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  • Reaction species: Human
  • Gene Name: CD3E T3E
  • Protein name: CD3, CD3E
  • Immunogen: Synthesized peptide derived from human CD3, CD3E
  • Specificity: The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g. In western blotting of Jurkat cell lysate, the antibody can label a 23KDa band corresponding to CD
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.60% sodium azide.
  • Source: Mouse, Monoclonal/IgG2a, Kappa
  • Dilution ratio: IHC-p 1:100-500, WB 1:200-1000, IF 1:100-500
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e)
  • Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],
  • Function: function:The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
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