• Neuron-Specific Enolase(NSE) rabbit mAb(ABT47R)
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Upingbio

YP-Ab-15504-100UL

Neuron-Specific Enolase(NSE) rabbit mAb(ABT47R)

Neuron-Specific Enolase(NSE) rabbit mAb(ABT47R)

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  • Reaction species: Human
  • Gene Name: ENO2
  • Protein name: Neuron-Specific Enolase(NSE)
  • Immunogen: Synthesized peptide derived from human Neuron-Specific Enolase(NSE)
  • Specificity: This antibody detects endogenous levels of Neuron-Specific Enolase(NSE) at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:200. IF 1:50-200
  • Purification process: The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: Gamma-enolase (EC 4.2.1.11;2-phospho-D-glycerate hydro-lyase;Enolase 2;Neural enolase;Neuron-specific enolase;NSE)
  • Function: catalytic activity:2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.,cofactor:Magnesium. Required for catalysis and for stabilizing the dimer.,developmental stage:During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.,function:Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.,induction:Levels of ENO2 increase dramatically in cardiovascular accidents, cerebral trauma, brain tumors and Creutzfeldt-Jacob disease.,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.,similarity:Belongs to the enolase family.,subcellular location:Can translocate to the plasma membrane
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