• BOB.1 rabbit mAb(ABT103R)
1 1

Upingbio

YP-Ab-15497-10UL

BOB.1 rabbit mAb(ABT103R)

BOB.1 rabbit mAb(ABT103R)

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  • Reaction species: Human
  • Gene Name: POU2AF1 OBF1
  • Protein name: BOB.1
  • Immunogen: Synthesized peptide derived from human BOB.1
  • Specificity: This antibody detects endogenous levels of BOB.1 at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:20. IF 1:50-200
  • Purification process: The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1;BOB-1;OCA-B;OCT-binding factor 1)
  • Function: disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.,
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