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Upingbio
SKU:YP-Ab-15493-100UL
Cytokeratin 19 (CK19) rabbit mAb(ABT166R)
Cytokeratin 19 (CK19) rabbit mAb(ABT166R)
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- Reaction species: Human
- Gene Name: KRT19
- Protein name: Cytokeratin 19 (CK19)
- Immunogen: Synthesized peptide derived from human Cytokeratin 19 (CK19)
- Specificity: This antibody detects endogenous levels of Cytokeratin 19 (CK19) at Human
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC-p 1:100-1:200. IF 1:50-200
- Purification process: The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
- Storage: -20°C/1 year
- Other Names: Keratin, type I cytoskeletal 19 (Cytokeratin-19;CK-19;Keratin-19;K19)
- Function: developmental stage:Present in hair follicles at all stages of development.,domain:This keratin differs from all other IF proteins in lacking the C-terminal tail domain.,function:Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein.,tissue specificity:Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestin
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