• CD105(Endoglin) rabbit mAb(ABT123R)
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Upingbio

YP-Ab-15491-100UL

CD105(Endoglin) rabbit mAb(ABT123R)

CD105(Endoglin) rabbit mAb(ABT123R)

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  • Reaction species: Human
  • Gene Name: ENG END
  • Protein name: CD105(Endoglin)
  • Immunogen: Synthesized peptide derived from human CD105(Endoglin)
  • Specificity: This antibody detects endogenous levels of CD105(Endoglin) at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:100. IF 1:50-200
  • Purification process: The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: Endoglin (CD antigen CD105)
  • Function: disease:Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.,function:Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.,subunit:Homodimer that forms an heteromeric complex with the signaling receptors for transforming growth factor-beta: TGF-beta receptors I and/or II. It
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