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Upingbio

SKU:YP-Ab-15484-10UL

CD21 rabbit mAb(ABT113R)

CD21 rabbit mAb(ABT113R)

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  • Reaction species: Human
  • Gene Name: CR2 C3DR
  • Protein name: CD21
  • Immunogen: Synthesized peptide derived from human CD21
  • Specificity: This antibody detects endogenous levels of CD21 at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:10. IF 1:50-200
  • Purification process: The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: Complement receptor type 2 (Cr2;Complement C3d receptor;Epstein-Barr virus receptor;EBV receptor;CD antigen CD21)
  • Function: disease:Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.,function:Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.,similarity:Belongs to the receptors of complement activation (RCA) family.,similarity:Contains 15 Sushi (CCP/SCR) domains.,tissue specificity:Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells
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