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Upingbio
SKU:YP-Ab-15435-10UL
S100A6 (ABT-S100A6) mouse mAb
S100A6 (ABT-S100A6) mouse mAb
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- Reaction species: Human; Predict react with Mouse, Rat
- Gene Name: S100A6 CACY
- Protein name: S100A6
- Immunogen: Synthesized peptide derived from human S100A6
- Specificity: This antibody detects endogenous levels of human S100A6. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Mouse, Monoclonal/IgG1, Kappa
- Dilution ratio: IHC-p 1:100-500. IF 1:50-200
- Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Storage: -20°C/1 year
- Background: S100 calcium binding protein A6(S100A6) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008],
- Function: induction:Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.,miscellaneous:This protein co-purified with the prolactin receptor.,PTM:The N-terminus is blocked.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer, antiparallel. Interacts with SUGT1.,
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