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Upingbio
SKU:YP-Ab-15364-100UL
N-Cadherin (ABT-CDH2) mouse mAb
N-Cadherin (ABT-CDH2) mouse mAb
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- Reaction species: Human
- Gene Name: CDH2 CDHN NCAD
- Protein name: Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
- Immunogen: Synthesized peptide derived from human N-Cadherin
- Specificity: This antibody detects endogenous levels of human N-Cadherin. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Mouse, Monoclonal/IgG2b, Kappa
- Dilution ratio: IHC-p 1:100-500,WB 1:500-2000. IF 1:50-200
- Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Storage: -20°C/1 year
- Background: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
- Function: function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,
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