• Villin (PT0254) mouse mAb
1 1

Upingbio

YP-Ab-15303-53UL

Villin (PT0254) mouse mAb

Villin (PT0254) mouse mAb

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  • Reaction species: Human;Mouse;Rat
  • Gene Name: VIL1 VIL
  • Protein name: Villin-1
  • Immunogen: Synthesized peptide derived from human Villin
  • Specificity: This antibody detects endogenous levels of human Villin. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Mouse, Monoclonal/IgG2b, Kappa
  • Dilution ratio: IHC-p 1:100-500，WB 1:500-2000
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008],
  • Function: domain:Consists of a large core fragment, the N-terminal portion, and a small headpiece, the C-terminal portion. The headpiece binds F-actin strongly in both the presence and absence of calcium.,function:Ca(2+)-regulated actin-binding protein.,similarity:Belongs to the villin/gelsolin family.,similarity:Contains 1 HP (headpiece) domain.,similarity:Contains 6 gelsolin-like repeats.,subunit:Monomer.,tissue specificity:Major component of microvilli of intestinal epithelial cells and kidney proximal tubule cells.,
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