• Synaptophysin (ABT533) Mouse mAb
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Upingbio

YP-Ab-15211-53UL

Synaptophysin (ABT533) Mouse mAb

Synaptophysin (ABT533) Mouse mAb

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  • Reaction species: Human;Mouse;Rat
  • Gene Name: SYP
  • Protein name: Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
  • Immunogen: Synthesized peptide derived from human Synaptophysin
  • Specificity: The antibody can specifically recognize human Synaptophysin protein.
  • Composition: PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
  • Source: Mouse, Monoclonal/IgG1, Kappa
  • Dilution ratio: IHC-p 1:200-400, WB 1:200-1000,
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Storage: -20°C
  • Other Names: Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
  • Background: This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],
  • Function: domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,
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