• PI 3-Kinase C2γ Polyclonal Antibody
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Upingbio

YP-Ab-15051-100UL

PI 3-Kinase C2γ Polyclonal Antibody

PI 3-Kinase C2γ Polyclonal Antibody

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  • Gene Name: PIK3C2G
  • Immunogen: Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ.
  • Specificity: PI 3-Kinase C2γ Polyclonal Antibody detects endogenous levels of PI 3-Kinase C2γ protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PIK3C2G; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma
  • Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
  • Function: catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate.,function:In vitro, phosphorylates PtdIns and PtdIns4P but not PtdIns(4,5)P2.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI3K/PI4K domain.,similarity:Contains 1 PX (phox homology) domain.,tissue specificity:Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC
  • Protein: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
  • DA: 160kD
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