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Upingbio
SKU:YP-Ab-14987-100UL
SgK288 Polyclonal Antibody
SgK288 Polyclonal Antibody
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- Gene Name: ANKK1
- Immunogen: The antiserum was produced against synthesized peptide derived from human ANKK1. AA range:321-370
- Specificity: SgK288 Polyclonal Antibody detects endogenous levels of SgK288 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: ANKK1; PKK2; SGK288; Ankyrin repeat and protein kinase domain-containing protein 1; Protein kinase PKK2; Sugen kinase 288; SgK288; X-kinase
- Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009],
- Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 12 ANK repeats.,tissue specificity:Highly expressed in brain and weakly expressed in placenta and spinal cord.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Ankyrin repeat and protein kinase domain-containing protein 1
- DA: 84kD
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