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SKU:YP-Ab-14911-100UL
PHKG1 Polyclonal Antibody
PHKG1 Polyclonal Antibody
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- Gene Name: PHKG1
- Immunogen: The antiserum was produced against synthesized peptide derived from human PHKG1. AA range:241-290
- Specificity: PHKG1 Polyclonal Antibody detects endogenous levels of PHKG1 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: PHKG1; PHKG; Phosphorylase b kinase gamma catalytic chain; skeletal muscle isoform; Phosphorylase kinase subunit gamma-1
- Background: This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
- Function: catalytic activity:2 ATP + phosphorylase b = 2 ADP + phosphorylase a.,domain:The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.,function:Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC
- Protein: Phosphorylase b kinase gamma catalytic chain skeletal muscle isoform
- DA: 45kD
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