• OXSR1 Polyclonal Antibody
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Upingbio

YP-Ab-14884-100UL

OXSR1 Polyclonal Antibody

OXSR1 Polyclonal Antibody

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  • Gene Name: OXSR1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human OXSR1. AA range:272-321
  • Specificity: OXSR1 Polyclonal Antibody detects endogenous levels of OXSR1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: OXSR1; KIAA1101; OSR1; Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein
  • Background: The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:By autophosphorylation on threonine.,function:Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.,tissue specificity:Ubiquitously expressed in all tissue examined.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Serine/threonine-protein kinase OSR1
  • DA: 50kD
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