• LOK Polyclonal Antibody
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Upingbio

YP-Ab-14818-100UL

LOK Polyclonal Antibody

LOK Polyclonal Antibody

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  • Gene Name: STK10
  • Immunogen: The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540
  • Specificity: LOK Polyclonal Antibody detects endogenous levels of LOK protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
  • Background: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Can act on substrates such as myelin basic protein and histone 2A on serine and threonine residues.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed predominantly in lymphoid organs.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA;IHC
  • Protein: Serine/threonine-protein kinase 10
  • DA: 120kD
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