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Upingbio

SKU:YP-Ab-14787-100UL

InsP 3-kinase B Polyclonal Antibody

InsP 3-kinase B Polyclonal Antibody

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  • Gene Name: ITPKB
  • Immunogen: Synthesized peptide derived from InsP 3-kinase B . at AA range: 130-210
  • Specificity: InsP 3-kinase B Polyclonal Antibody detects endogenous levels of InsP 3-kinase B protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ITPKB; Inositol-trisphosphate 3-kinase B; Inositol 1; 4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase B
  • Background: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,enzyme regulation:IP3K is activated by calmodulin. Form B is much more sensitive to calcium/calmodulin than form A.,similarity:Belongs to the inositol phosphokinase (IPK) family.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: Inositol-trisphosphate 3-kinase B
  • DA: 100kD
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