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Upingbio
SKU:YP-Ab-14766-100UL
GRK 5 Polyclonal Antibody
GRK 5 Polyclonal Antibody
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- Gene Name: GRK5
- Immunogen: The antiserum was produced against synthesized peptide derived from human GRK5. AA range:351-400
- Specificity: GRK 5 Polyclonal Antibody detects endogenous levels of GRK 5 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: GRK5; GPRK5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5
- Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008],
- Function: catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.,function:Specifically phosphorylates the activated forms of G protein-coupled receptors.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: G protein-coupled receptor kinase 5
- DA: 68kD
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