• GAP1-InsP4 BP Polyclonal Antibody
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Upingbio

YP-Ab-14753-100UL

GAP1-InsP4 BP Polyclonal Antibody

GAP1-InsP4 BP Polyclonal Antibody

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  • Gene Name: RASA3
  • Immunogen: The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296
  • Specificity: GAP1-InsP4 BP Polyclonal Antibody detects endogenous levels of GAP1-InsP4 BP protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein
  • Background: This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
  • Function: function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 2 C2 domains.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: Ras GTPase-activating protein 3
  • DA: 95kD
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