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Upingbio
SKU:YP-Ab-14677-100UL
Blk Polyclonal Antibody
Blk Polyclonal Antibody
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- Gene Name: BLK
- Immunogen: The antiserum was produced against synthesized peptide derived from human BLK. AA range:456-505
- Specificity: Blk Polyclonal Antibody detects endogenous levels of Blk protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk
- Background: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
- Function: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May function in a signal transduction pathway that is restricted to B-lymphoid cells.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: Tyrosine-protein kinase Blk
- DA: 58kD
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