• c-Yes Monoclonal Antibody
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Upingbio

YP-Ab-14134-53UL

c-Yes Monoclonal Antibody

c-Yes Monoclonal Antibody

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  • Reaction species: Human
  • Gene Name: YES1
  • Protein name: Proto-oncogene tyrosine-protein kinase Yes
  • Immunogen: Purified recombinant fragment of c-Yes (aa10-193) expressed in E. Coli.
  • Specificity: c-Yes Monoclonal Antibody detects endogenous levels of c-Yes protein.
  • Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: Affinity purification
  • Storage: -20°C/1 year
  • Other Names: YES1; YES; Tyrosine-protein kinase Yes; Proto-oncogene c-Yes; p61-Yes
  • Background: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.,
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