• CD244 Polyclonal Antibody
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YP-Ab-14067-100UL

CD244 Polyclonal Antibody

CD244 Polyclonal Antibody

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  • Gene Name: CD244
  • Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD244. AA range:101-150
  • Specificity: CD244 Polyclonal Antibody detects endogenous levels of CD244 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CD244; 2B4; Natural killer cell receptor 2B4; NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; CD244
  • Background: This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],
  • Function: function:Modulate other receptor-ligand interactions to enhance leukocyte activation.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD48. Following phosphorylation, it is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. Binding of SH2D1A/SAP to CD244 prevents its association with PTPN11/SHP-2.,tissue specificity:Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Natural killer cell receptor 2B4
  • DA: 42kD
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