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Upingbio
SKU:YP-Ab-13951-100UL
NKp30 Polyclonal Antibody
NKp30 Polyclonal Antibody
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- Gene Name: NCR3
- Immunogen: The antiserum was produced against synthesized peptide derived from human NCR3. AA range:104-153
- Specificity: NKp30 Polyclonal Antibody detects endogenous levels of NKp30 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: NCR3; 1C7; LY117; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NKp30; CD antigen CD337
- Background: The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010],
- Function: function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,polymorphism:A genetic variation in NCR3 is associated with mild malaria suceptibility [MIM:609148].,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subunit:Interacts with CD3Z.,tissue specificity:Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.,
- Species: Human;Rat
- Range: WB;ELISA
- Protein: Natural cytotoxicity triggering receptor 3
- DA: 30kD
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