• HLA-DPα1 Polyclonal Antibody
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Upingbio

YP-Ab-13931-100UL

HLA-DPα1 Polyclonal Antibody

HLA-DPα1 Polyclonal Antibody

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  • Gene Name: HLA-DPA1
  • Immunogen: Synthesized peptide derived from the Internal region of human HLA-DPα1.
  • Specificity: HLA-DPα1 Polyclonal Antibody detects endogenous levels of HLA-DPα1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: HLA-DPA1; HLA-DP1A; HLASB; HLA class II histocompatibility antigen; DP alpha 1 chain; DP(W3); DP(W4); HLA-SB alpha chain; MHC class II DP3-alpha; MHC class II DPA1
  • Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008],
  • Function: similarity:Belongs to the MHC class II family.,
  • Species: Human
  • Range: WB;ELISA
  • Protein: HLA class II histocompatibility antigen DP alpha 1 chain
  • DA: 29kD
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